Imaging Biomarker Services

Bioxydyn provides high-standard, quantitative MRI imaging services to the pharmaceutical industry and for clinical/academic R&D in small or large multi-centre studies.

Bioxydyn’s accurate, reliable imaging biomarkers are based on scientifically leading techniques and efficient, high-quality imaging study management processes. Bioxydyn gives unique insight into disease progression and drug effects, helps pharmaceutical companies make investment decisions and assists clinicians in developing the best treatment for patients.

Imaging Biomarker Services

Bioxydyn provides high-standard, quantitative MRI imaging services to the pharmaceutical industry and for clinical/academic R&D in small or large multi-centre studies.

Bioxydyn’s accurate, reliable imaging biomarkers are based on scientifically leading techniques and efficient, high-quality imaging study management processes. Bioxydyn gives unique insight into disease progression and drug effects, helps pharmaceutical companies make investment decisions and assists clinicians in developing the best treatment for patients.

Quantitative Imaging Biomarkers

The imaging CRO service provided by Bioxydyn focusses on quantitative biomarkers derived from magnetic resonance imaging (MRI). MRI provides a powerful insight into disease and drug effects that is safe and non-invasive. Thanks to the lack of ionising radiation, MRI provides a unique opportunity to investigate multiple time-points and to explore the evolution of treatments and diseases. The excellent safety profile allows for the study of the most sensitive patient groups.

Quantitative imaging biomarkers extract measurable features from medical data. They are capable of producing repeatable, validated results providing outstanding clinical information with smaller patient populations.

Cancer imaging

Bioxydyn provides advanced functional MRI biomarkers in oncology, using techniques such as diffusion MRI and dynamic contrast-enhanced (DCE) MRI, and is the leading CRO offering tumor hypoxia imaging to inform therapy effectiveness or characterise tumour physiology.

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Respiratory function imaging

Bioxydyn offers imaging biomarkers in respiratory diseases such as pulmonary embolism, asthma, pulmonary hypertension, interstitial disease and COPD. We are the world leaders in delivering oxygen-enhanced MRI (OE-MRI) for imaging lung function.

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Inflammation

Bioxydyn has delivered multiple studies for pharmaceutical companies in the quantitative imaging of inflammation in a wide range of diseases, including rheumatoid arthritis and osteoarthritis.

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Neuroimaging

Bioxydyn is experienced in the deployment of quantitative MRI methods for neuroscience in conditions including stroke, neurodevelopmental conditions, multiple sclerosis, dementia and neuro-oncology.

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Liver imaging

Bioxydyn offers dynamic MRI measurement of liver transporter fluxes, MR-PDFF and MR elastography in the investigation of liver disease, including NASH.

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Bioxydyn's imaging service

Innovative study design

Bioxydyn helps design studies and flexibly adapts its tools to the requirements of new studies and techniques.

Site set-up and qualification

Bioxydyn can establish the sponsor’s choice of sites to the study and provides on-site or remote training to ensure high quality image acquisition.

Image quality control

Bioxydyn checks images as they arrive and feeds back to the site so that high quality acquisition and calibration is maintained.

Analysis

Using VoxelFlow, a proprietary in-house analysis and study management platform, Bioxydyn produces biomarker measurements that are reliable, repeatable and auditable.

Comprehensive reporting

Bioxydyn returns data, processed images and, where requested, scientific interpretation according to customer requirements.

A global reach

Bioxydyn trains and works with any imaging site defined by the customer following a simple electronic qualification process. Most globally installed MRI equipment can be set up to perform our quantitative methods, but Bioxydyn can provide quick and accurate assurance.

Whatever the study protocol, Bioxydyn can work with your preferred imaging sites, or suggest alternatives.


Over a decade of reliable service provision

Founded in 2009, Bioxydyn has a strong track record in the delivery of imaging services in clinical trials.

Bioxydyn has delivered numerous studies for multiple pharma/biotech and clinical/academic clients. Bioxydyn also has a strong track record in supporting, winning and delivering grant funded studies.

How can we help?

Contact us at info@bioxydyn.com