Selected publications from Bioxydyn and our close collaborators

Canales-Rodríguez EJ, Pizzolato M, Zhou FL, Barakovic M, Thiran JP, Jones DK, Parker GJM, Dyrby TB, Pore size estimation in axon-mimicking microfibers with diffusion-relaxation MRI. Magn Reson Med. 2024 Jun;91(6):2579-2596.

Shalom ES, Kim H, van der Heijden RA, Ahmed Z, Patel R, Hormuth DA 2nd, DiCarlo JC, Yankeelov TE, Sisco NJ, Dortch RD, Stokes AM, Inglese M, Grech-Sollars M, Toschi N, Sahoo P, Singh A, Verma SK, Rathore DK, Kazerouni AS, Partridge SC, LoCastro E, Paudyal R, Wolansky IA, Shukla-Dave A, Schouten P, Gurney-Champion OJ, Jiřík R, Macíček O, Bartoš M, Vitouš J, Das AB, Kim SG, Bokacheva L, Mikheev A, Rusinek H, Berks M, Hubbard Cristinacce PL, Little RA, Cheung S, O'Connor JPB, Parker GJM, Moloney B, LaViolette PS, Bobholz S, Duenweg S, Virostko J, Laue HO, Sung K, Nabavizadeh A, Saligheh Rad H, Hu LS, Sourbron S, Bell LC, Fathi Kazerooni A, The ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): Results from the OSIPI-Dynamic Contrast-Enhanced challenge. Magn Reson Med. 2024 May;91(5):1803-1821.

Kim M, Naish JH, Needleman SH, Tibiletti M, Taylor Y, O'Connor JPB, Parker GJM, Feasibility of dynamic T2*-based oxygen-enhanced lung MRI at 3T. Magn Reson Med. 2024 Mar;91(3):972-986.

Ravi D, Alzheimer’s Disease Neuroimaging Initiative, Barkhof F, Alexander DC, Puglisi L, Parker GJM, Eshaghi A, An efficient semi-supervised quality control system trained using physics-based MRI-artefact generators and adversarial training. Med Image Anal. 2024 Jan;91:103033.

Needleman SH, Kim M, McClelland JR, Naish JH, Tibiletti M, O'Connor JPB, Parker GJM, Independent component analysis (ICA) applied to dynamic oxygen-enhanced MRI (OE-MRI) for robust functional lung imaging at 3 T. Magn Reson Med. 2024 Mar;91(3):955-971.

Powell E, Dickie BR, Ohene Y, Maskery M, Parker GJM, Parkes LM, Blood-brain barrier water exchange measurements using contrast-enhanced ASL. NMR Biomed. 2023 Nov;36(11):e5009.

Edwards L, Waterton JC, Naish J, Short C, Semple T, Jm Parker G, Tibiletti M, Imaging human lung perfusion with contrast media: A meta-analysis. Eur J Radiol. 2023 Jul;164:110850.

Ohene Y, Harris WJ, Powell E, Wycech NW, Smethers KF, Lasič S, South K, Coutts G, Sharp A, Lawrence CB, Boutin H, Parker GJM, Parkes LM, Dickie BR, Filter exchange imaging with crusher gradient modelling detects increased blood-brain barrier water permeability in response to mild lung infection. Fluids Barriers CNS. 2023 Apr 3;20(1):25.

Teh I, Shelley D, Boyle JH, Zhou F, Poenar AM, Sharrack N, Foster RJ, Yuldasheva NY, Parker GJM, Dall'Armellina E, Plein S, Schneider JE, Szczepankiewicz F, Cardiac q-space trajectory imaging by motion-compensated tensor-valued diffusion encoding in human heart in vivo. Magn Reson Med. 2023 Jul;90(1):150-165.

Powell E, Ohene Y, Battiston M, Dickie BR, Parkes LM, Parker GJM, Blood-brain barrier water exchange measurements using FEXI: Impact of modeling paradigm and relaxation time effects. Magn Reson Med. 2023 Jul;90(1):34-50.

Dubec MJ, Buckley DL, Berks M, Clough A, Gaffney J, Datta A, McHugh DJ, Porta N, Little RA, Cheung S, Hague C, Eccles CL, Hoskin PJ, Bristow RG, Matthews JC, van Herk M, Choudhury A, Parker GJM, McPartlin A, O'Connor JPB, First-in-human technique translation of oxygen-enhanced MRI to an MR Linac system in patients with head and neck cancer. Radiother Oncol. 2023 Jun;183:109592.

Tibiletti M, Eaden JA, Naish JH, Hughes PJC, Waterton JC, Heaton MJ, Chaudhuri N, Skeoch S, Bruce IN, Bianchi S, Wild JM, Parker GJM, Imaging biomarkers of lung ventilation in interstitial lung disease from 129Xe and oxygen enhanced 1H MRI. Magn Reson Imaging. 2023 Jan;95:39-49.

Hubbard Cristinacce PL, Keaveney S, Aboagye EO, Hall MG, Little RA, O'Connor JPB, Parker GJM, Waterton JC, Winfield JM, Jauregui-Osoro M, Clinical translation of quantitative magnetic resonance imaging biomarkers - An overview and gap analysis of current practice. Phys Med. 2022 Sep;101:165-182.

Dickie BR, Jin T, Wang P, Hinz R, Harris W, Boutin H, Parker GJ, Parkes LM, Matthews JC, Quantitative kinetic modelling and mapping of cerebral glucose transport and metabolism using glucoCESL MRI. J Cereb Blood Flow Metab. 2022 Nov;42(11):2066-2079.

Jandric D, Parker GJM, Haroon H, Tomassini V, Muhlert N, Lipp I, A tractometry principal component analysis of white matter tract network structure and relationships with cognitive function in relapsing-remitting multiple sclerosis. Neuroimage Clin. 2022;34:102995.

Cheriyan J, Roberts A, Roberts C, Graves MJ, Patterson I, Slough RA, Schroyer R, Fernando D, Kumar S, Lee S, Parker GJM, Sarov-Blat L, McEniery C, Middlemiss J, Sprecher D, Janiczek RL, Evaluation of Dynamic Contrast-Enhanced MRI Measures of Lung Congestion and Endothelial Permeability in Heart Failure: A Prospective Method Validation Study. J Magn Reson Imaging. 2022 Aug;56(2):450-461.

Tadimalla S, Wilson DJ, Shelley D, Bainbridge G, Saysell M, Mendichovszky IA, Graves MJ, Guthrie JA, Waterton JC, Parker GJM, Sourbron SP, Bias, Repeatability and Reproducibility of Liver T(1) Mapping With Variable Flip Angles. J Magn Reson Imaging. 2022 Oct;56(4):1042-1052.

Alyami A, Hoad CL, Tench C, Bannur U, Clarke C, Latief K, Argyriou K, Lobo A, Lung P, Baldwin-Cleland R, Sahnan K, Hart A, Limdi JK, Mclaughlin J, Atkinson D, Parker GJM, O'Connor JPB, Little RA, Gowland PA, Moran GW, Quantitative Magnetic Resonance Imaging in Perianal Crohn's Disease at 1.5 and 3.0 T: A Feasibility Study. Diagnostics (Basel). 2021 Nov 17;11(11):.

Jandric D, Lipp I, Paling D, Rog D, Castellazzi G, Haroon H, Parkes L, Parker GJM, Tomassini V, Muhlert N, Mechanisms of Network Changes in Cognitive Impairment in Multiple Sclerosis. Neurology. 2021 Nov 9;97(19):e1886-e1897.

Jandric D, Doshi A, Scott R, Paling D, Rog D, Chataway J, Schoonheim MM, Parker G, Muhlert N, A Systematic Review of Resting-State Functional MRI Connectivity Changes and Cognitive Impairment in Multiple Sclerosis. Brain Connect. 2022 Mar;12(2):112-133.

Kerkelä L, Nery F, Callaghan R, Zhou F, Gyori NG, Szczepankiewicz F, Palombo M, Parker GJM, Zhang H, Hall MG, Clark CA, Comparative analysis of signal models for microscopic fractional anisotropy estimation using q-space trajectory encoding. Neuroimage. 2021 Nov 15;242:118445.

Manning C, Stringer M, Dickie B, Clancy U, Valdés Hernandez MC, Wiseman SJ, Garcia DJ, Sakka E, Backes WH, Ingrisch M, Chappell F, Doubal F, Buckley C, Parkes LM, Parker GJM, Marshall I, Wardlaw JM, Thrippleton MJ, Sources of systematic error in DCE-MRI estimation of low-level blood-brain barrier leakage. Magn Reson Med. 2021 Oct;86(4):1888-1903.

Berks M, Little RA, Watson Y, Cheung S, Datta A, O'Connor JPB, Scaramuzza D, Parker GJM, A model selection framework to quantify microvascular liver function in gadoxetate-enhanced MRI: Application to healthy liver, diseased tissue, and hepatocellular carcinoma. Magn Reson Med. 2021 Oct;86(4):1829-1844.

Huang CC, Hsu CH, Zhou FL, Kusmia S, Drakesmith M, Parker GJM, Lin CP, Jones DK, Validating pore size estimates in a complex microfiber environment on a human MRI system. Magn Reson Med. 2021 Sep;86(3):1514-1530.

Mahmood RD, Shaw D, Descamps T, Zhou C, Morgan RD, Mullamitha S, Saunders M, Mescallado N, Backen A, Morris K, Little RA, Cheung S, Watson Y, O'Connor JPB, Jackson A, Parker GJM, Dive C, Jayson GC, Effect of oxaliplatin plus 5-fluorouracil or capecitabine on circulating and imaging biomarkers in patients with metastatic colorectal cancer: a prospective biomarker study. BMC Cancer. 2021 Apr 1;21(1):354.

McFadden JJ, Matthews JC, Scott LA, Parker GJM, Lohézic M, Parkes LM, Optimization of quantitative susceptibility mapping for regional estimation of oxygen extraction fraction in the brain. Magn Reson Med. 2021 Sep;86(3):1314-1329.

Dickie BR, Boutin H, Parker GJM, Parkes LM, Alzheimer's disease pathology is associated with earlier alterations to blood-brain barrier water permeability compared with healthy ageing in TgF344-AD rats. NMR Biomed. 2021 Jul;34(7):e4510.

Zhou FL, McHugh DJ, Li Z, Gough JE, Williams GR, Parker GJM, Coaxial electrospun biomimetic copolymer fibres for application in diffusion magnetic resonance imaging. Bioinspir Biomim. 2021 Jun 14;16(4):.

MacKay JW, Nezhad FS, Rifai T, Kaggie JD, Naish JH, Roberts C, Graves MJ, Waterton JC, Janiczek RL, Roberts AR, McCaskie A, Gilbert FJ, Parker GJM, Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study. Eur Radiol. 2021 Aug;31(8):5746-5758.

McHugh DJ, Porta N, Little RA, Cheung S, Watson Y, Parker GJM, Jayson GC, O'Connor JPB, Image Contrast, Image Pre-Processing, and T1 Mapping Affect MRI Radiomic Feature Repeatability in Patients with Colorectal Cancer Liver Metastases. Cancers (Basel). 2021 Jan 11;13(2):.

Al-Bachari S, Naish JH, Parker GJM, Emsley HCA, Parkes LM, Blood-Brain Barrier Leakage Is Increased in Parkinson's Disease. Front Physiol. 2020;11:593026.

Scott LA, Dickie BR, Rawson SD, Coutts G, Burnett TL, Allan SM, Parker GJ, Parkes LM, Characterisation of microvessel blood velocity and segment length in the brain using multi-diffusion-time diffusion-weighted MRI. J Cereb Blood Flow Metab. 2021 Aug;41(8):1939-1953.

Bajada CJ, Costa Campos LQ, Caspers S, Muscat R, Parker GJM, Lambon Ralph MA, Cloutman LL, Trujillo-Barreto NJ, A tutorial and tool for exploring feature similarity gradients with MRI data. Neuroimage. 2020 Nov 1;221:117140.

Jacob J, Alexander D, Baillie JK, Berka R, Bertolli O, Blackwood J, Buchan I, Bloomfield C, Cushnan D, Docherty A, Edey A, Favaro A, Gleeson F, Halling-Brown M, Hare S, Jefferson E, Johnstone A, Kirby M, McStay R, Nair A, Openshaw PJM, Parker G, Reilly G, Robinson G, Roditi G, Rodrigues JCL, Sebire N, Semple MG, Sudlow C, Woznitza N, Joshi I, Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database. Eur Respir J. 2020 Aug;56(2):.

Dickie BR, Parker GJM, Parkes LM, Measuring water exchange across the blood-brain barrier using MRI. Prog Nucl Magn Reson Spectrosc. 2020 Feb;116:19-39.

McHugh DJ, Lipowska-Bhalla G, Babur M, Watson Y, Peset I, Mistry HB, Hubbard Cristinacce PL, Naish JH, Honeychurch J, Williams KJ, O'Connor JPB, Parker GJM, Diffusion model comparison identifies distinct tumor sub-regions and tracks treatment response. Magn Reson Med. 2020 Sep;84(3):1250-1263.

Mitsides N, Alsehli FMS, Mc Hough D, Shalamanova L, Wilkinson F, Alderdice J, Mitra R, Swiecicka A, Brenchley P, Parker GJM, Alexander MY, Mitra S, Salt and Water Retention Is Associated with Microinflammation and Endothelial Injury in Chronic Kidney Disease. Nephron. 2019;143(4):234-242.

Bajada CJ, Trujillo-Barreto NJ, Parker GJM, Cloutman LL, Lambon Ralph MA, A structural connectivity convergence zone in the ventral and anterior temporal lobes: Data-driven evidence from structural imaging. Cortex. 2019 Nov;120:298-307.

Lundell H, Nilsson M, Dyrby TB, Parker GJM, Cristinacce PLH, Zhou FL, Topgaard D, Lasič S, Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail. Sci Rep. 2019 Jun 21;9(1):9026.

Mitsides N, McHugh D, Swiecicka A, Mitra R, Brenchley P, Parker GJM, Mitra S, Extracellular resistance is sensitive to tissue sodium status; implications for bioimpedance-derived fluid volume parameters in chronic kidney disease. J Nephrol. 2020 Feb;33(1):119-127.

Salem A, Little RA, Latif A, Featherstone AK, Babur M, Peset I, Cheung S, Watson Y, Tessyman V, Mistry H, Ashton G, Behan C, Matthews JC, Asselin MC, Bristow RG, Jackson A, Parker GJM, Faivre-Finn C, Williams KJ, O'Connor JPB, Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non-small Cell Lung Cancer. Clin Cancer Res. 2019 Jul 1;25(13):3818-3829.

Riemer F, McHugh D, Zaccagna F, Lewis D, McLean MA, Graves MJ, Gilbert FJ, Parker GJM, Gallagher FA, Measuring tissue sodium concentration: Cross-vendor repeatability and reproducibility of 23Na-MRI across two sites. J Magn Reson Imaging. 2019 Oct;50(4):1278-1284.

Whitley CB, Vijay S, Yao B, Pineda M, Parker GJM, Rojas-Caro S, Zhang X, Dai Y, Cinar A, Bubb G, Patki KC, Escolar ML, Final results of the phase 1/2, open-label clinical study of intravenous recombinant human N-acetyl-α-d-glucosaminidase (SBC-103) in children with mucopolysaccharidosis IIIB. Mol Genet Metab. 2019 Feb;126(2):131-138.

Busby N, Halai AD, Parker GJM, Coope DJ, Lambon Ralph MA, Mapping whole brain connectivity changes: The potential impact of different surgical resection approaches for temporal lobe epilepsy. Cortex. 2019 Apr;113:1-14.

Jayson GC, Zhou C, Backen A, Horsley L, Marti-Marti K, Shaw D, Mescallado N, Clamp A, Saunders MP, Valle JW, Mullamitha S, Braun M, Hasan J, McEntee D, Simpson K, Little RA, Watson Y, Cheung S, Roberts C, Ashcroft L, Manoharan P, Scherer SJ, Del Puerto O, Jackson A, O'Connor JPB, Parker GJM, Dive C, Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer. Nat Commun. 2018 Nov 7;9(1):4672.

O'Connor JPB, Robinson SP, Waterton JC, Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI. Br J Radiol. 2019 Mar;92(1095):20180642.

Datta A, Aznar MC, Dubec M, Parker GJM, O'Connor JPB, Delivering Functional Imaging on the MRI-Linac: Current Challenges and Potential Solutions. Clin Oncol. 2018 Nov;30(11):702-710.

Dickie BR, Vandesquille M, Ulloa J, Boutin H, Parkes LM, Parker GJM, Water-exchange MRI detects subtle blood-brain barrier breakdown in Alzheimer's disease rats. Neuroimage. 2019 Jan 1;184:349-358.

Grech-Sollars M, Zhou FL, Waldman AD, Parker GJM, Hubbard Cristinacce PL, Stability and reproducibility of co-electrospun brain-mimicking phantoms for quality assurance of diffusion MRI sequences. Neuroimage. 2018 Nov 1;181:395-402.

Little RA, Jamin Y, Boult JKR, Naish JH, Watson Y, Cheung S, Holliday KF, Lu H, McHugh DJ, Irlam J, West CML, Betts GN, Ashton G, Reynolds AR, Maddineni S, Clarke NW, Parker GJM, Waterton JC, Robinson SP, O'Connor JPB, Mapping Hypoxia in Renal Carcinoma with Oxygen-enhanced MRI: Comparison with Intrinsic Susceptibility MRI and Pathology. Radiology. 2018 Sep;288(3):739-747.

Martini K, Gygax CM, Benden C, Morgan AR, Parker GJM, Frauenfelder T, Volumetric dynamic oxygen-enhanced MRI (OE-MRI): comparison with CT Brody score and lung function in cystic fibrosis patients. Eur Radiol. 2018 Oct;28(10):4037-4047.

Little RA, Barjat H, Hare JI, Jenner M, Watson Y, Cheung S, Holliday K, Zhang W, O'Connor JPB, Barry ST, Puri S, Parker GJM, Waterton JC, Evaluation of dynamic contrast-enhanced MRI biomarkers for stratified cancer medicine: How do permeability and perfusion vary between human tumours? Magn Reson Imaging. 2018 Feb;46:98-105.

McHugh DJ, Zhou FL, Wimpenny I, Poologasundarampillai G, Naish JH, Hubbard Cristinacce PL, Parker GJM, A biomimetic tumor tissue phantom for validating diffusion-weighted MRI measurements. Magn Reson Med. 2018 Jul;80(1):147-158.

Abid KA, Sobowale OA, Parkes LM, Naish J, Parker GJM, du Plessis D, Brough D, Barrington J, Allan SM, Hinz R, Parry-Jones AR, Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI. J Neuroimaging. 2018 Mar;28(2):158-161.

Featherstone AK, O'Connor JPB, Little RA, Watson Y, Cheung S, Babur M, Williams KJ, Matthews JC, Parker GJM, Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI. Magn Reson Med. 2018 Apr;79(4):2236-2245.

Skeoch S, Hubbard Cristinacce PL, Dobbs M, Naish J, Woodhouse N, Ho M, Waterton JC, Parker GJM, Bruce IN, Evaluation of non-contrast MRI biomarkers in lupus nephritis. Clin Exp Rheumatol. 2017 Nov-Dec;35(6):954-958.

Tomaszewski MR, Gonzalez IQ, O'Connor JP, Abeyakoon O, Parker GJ, Williams KJ, Gilbert FJ, Bohndiek SE, Oxygen Enhanced Optoacoustic Tomography (OE-OT) Reveals Vascular Dynamics in Murine Models of Prostate Cancer. Theranostics. 2017;7(11):2900-2913.

Waterton JC, Ho M, Nordenmark LH, Jenkins M, DiCarlo J, Guillard G, Roberts C, Buonaccorsi G, Parker GJM, Bowes MA, Peterfy C, Kellner H, Taylor PC, Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting. Eur Radiol. 2017 Sep;27(9):3662-3668.

O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, [...], Waterton JC, Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol. 2017 Mar;14(3):169-186.

Bajada CJ, Haroon HA, Azadbakht H, Parker GJM, Lambon Ralph MA, Cloutman LL, The tract terminations in the temporal lobe: Their location and associated functions. Cortex. 2017 Dec;97:277-290.

Alamidi DF, Kindvall SS, Hubbard Cristinacce PL, McGrath DM, Young SS, Naish JH, Waterton JC, Wollmer P, Diaz S, Olsson M, Hockings PD, Lagerstrand KM, Parker GJ, Olsson LE, T1 Relaxation Time in Lungs of Asymptomatic Smokers. PLoS One. 2016;11(3):e0149760.

Mills SJ, du Plessis D, Pal P, Thompson G, Buonacorrsi G, Soh C, Parker GJ, Jackson A, Mitotic Activity in Glioblastoma Correlates with Estimated Extravascular Extracellular Space Derived from Dynamic Contrast-Enhanced MR Imaging. AJNR Am J Neuroradiol. 2016 May;37(5):811-7.

O'Connor JP, Boult JK, Jamin Y, Babur M, Finegan KG, Williams KJ, Little RA, Jackson A, Parker GJ, Reynolds AR, Waterton JC, Robinson SP, Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models. Cancer Res. 2016 Feb 15;76(4):787-95.

Zhang WJ, Niven RM, Young SS, Liu YZ, Parker GJ, Naish JH, T1-weighted Dynamic Contrast-enhanced MR Imaging of the Lung in Asthma: Semiquantitative Analysis for the Assessment of Contrast Agent Kinetic Characteristics. Radiology. 2016 Mar;278(3):906-16.

Alamidi DF, Morgan AR, Hubbard Cristinacce PL, Nordenmark LH, Hockings PD, Lagerstrand KM, Young SS, Naish JH, Waterton JC, Maguire NC, Olsson LE, Parker GJ, COPD Patients Have Short Lung Magnetic Resonance T1 Relaxation Time. COPD. 2016;13(2):153-9.

Tiddens HA, Stick SM, Wild JM, Ciet P, Parker GJ, Koch A, Vogel-Claussen J, Respiratory tract exacerbations revisited: ventilation, inflammation, perfusion, and structure (VIPS) monitoring to redefine treatment. Pediatr Pulmonol. 2015 Oct;50 Suppl 40:S57-65.

Teh I, Zhou FL, Hubbard Cristinacce PL, Parker GJ, Schneider JE, Biomimetic phantom for cardiac diffusion MRI. J Magn Reson Imaging. 2016 Mar;43(3):594-600.

Zhang WJ, Hubbard Cristinacce PL, Bondesson E, Nordenmark LH, Young SS, Liu YZ, Singh D, Naish JH, Parker GJ, MR Quantitative Equilibrium Signal Mapping: A Reliable Alternative to CT in the Assessment of Emphysema in Patients with Chronic Obstructive Pulmonary Disease. Radiology. 2015 May;275(2):579-88.

Zhang WJ, Niven RM, Young SS, Liu YZ, Parker GJ, Naish JH, Dynamic oxygen-enhanced magnetic resonance imaging of the lung in asthma -- initial experience. Eur J Radiol. 2015 Feb;84(2):318-26.

O'Connor JP, Rose CJ, Waterton JC, Carano RA, Parker GJ, Jackson A, Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome. Clin Cancer Res. 2015 Jan 15;21(2):249-57.

Morgan AR, Parker GJ, Roberts C, Buonaccorsi GA, Maguire NC, Hubbard Cristinacce PL, Singh D, Vestbo J, Bjermer L, Jögi J, Taib Z, Sarv J, Bruijnzeel PL, Olsson LE, Bondesson E, Nihlén U, McGrath DM, Young SS, Waterton JC, Nordenmark LH, Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD. Eur J Radiol. 2014 Nov;83(11):2093-101.

Miller CA, Naish JH, Shaw SM, Yonan N, Williams SG, Clark D, Bishop PW, Ainslie MP, Borg A, Coutts G, Parker GJ, Ray SG, Schmitt M, Multiparametric cardiovascular magnetic resonance surveillance of acute cardiac allograft rejection and characterisation of transplantation-associated myocardial injury: a pilot study. J Cardiovasc Magn Reson. 2014 Jul 20;16(1):52.

Ferl GZ, O'Connor JP, Parker GJ, Carano RA, Acharya SJ, Jayson GC, Port RE, Mixed-effects modeling of clinical DCE-MRI data: application to colorectal liver metastases treated with bevacizumab. J Magn Reson Imaging. 2015 Jan;41(1):132-41.

Lyksborg M, Siebner HR, Sørensen PS, Blinkenberg M, Parker GJ, Dogonowski AM, Garde E, Larsen R, Dyrby TB, Secondary progressive and relapsing remitting multiple sclerosis leads to motor-related decreased anatomical connectivity. PLoS One. 2014;9(4):e95540.

Hubbard PL, Zhou FL, Eichhorn SJ, Parker GJ, Biomimetic phantom for the validation of diffusion magnetic resonance imaging. Magn Reson Med. 2015 Jan;73(1):299-305.

Miller CA, Naish JH, Ainslie MP, Tonge C, Tout D, Arumugam P, Banerji A, Egdell RM, Clark D, Weale P, Steadman CD, McCann GP, Ray SG, Parker GJ, Schmitt M, Voxel-wise quantification of myocardial blood flow with cardiovascular magnetic resonance: effect of variations in methodology and validation with positron emission tomography. J Cardiovasc Magn Reson. 2014 Jan 24;16(1):11.

Miller CA, Sarma J, Naish JH, Yonan N, Williams SG, Shaw SM, Clark D, Pearce K, Stout M, Potluri R, Borg A, Coutts G, Chowdhary S, McCann GP, Parker GJ, Ray SG, Schmitt M, Multiparametric cardiovascular magnetic resonance assessment of cardiac allograft vasculopathy. J Am Coll Cardiol. 2014 Mar 4;63(8):799-808.

Horsley L, Cummings J, Middleton M, Ward T, Backen A, Clamp A, Dawson M, Farmer H, Fisher N, Halbert G, Halford S, Harris A, Hasan J, Hogg P, Kumaran G, Little R, Parker GJ, Potter P, Saunders M, Roberts C, Shaw D, Smith N, Smythe J, Taylor A, Turner H, Watson Y, Dive C, Jayson GC, Cancer Research UK Drug Development Office Phase I clinical trial, A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemother Pharmacol. 2013 Dec;72(6):1343-52.

Linnik IV, Scott ML, Holliday KF, Woodhouse N, Waterton JC, O'Connor JP, Barjat H, Liess C, Ulloa J, Young H, Dive C, Hodgkinson CL, Ward T, Roberts D, Mills SJ, Thompson G, Buonaccorsi GA, Cheung S, Jackson A, Naish JH, Parker GJ, Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma. Magn Reson Med. 2014 May;71(5):1854-62.

Rose CJ, O'Connor JP, Cootes TF, Taylor CJ, Jayson GC, Parker GJ, Waterton JC, Indexed distribution analysis for improved significance testing of spatially heterogeneous parameter maps: application to dynamic contrast-enhanced MRI biomarkers. Magn Reson Med. 2014 Mar;71(3):1299-311.

Ulloa JL, Stahl S, Yates J, Woodhouse N, Kenna JG, Jones HB, Waterton JC, Hockings PD, Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition. NMR Biomed. 2013 Oct;26(10):1258-70.

Miller CA, Naish JH, Bishop P, Coutts G, Clark D, Zhao S, Ray SG, Yonan N, Williams SG, Flett AS, Moon JC, Greiser A, Parker GJ, Schmitt M, Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume. Circ Cardiovasc Imaging. 2013 May 1;6(3):373-83.

Bozzali M, Spanò B, Parker GJ, Giulietti G, Castelli M, Basile B, Rossi S, Serra L, Magnani G, Nocentini U, Caltagirone C, Centonze D, Cercignani M, Anatomical brain connectivity can assess cognitive dysfunction in multiple sclerosis. Mult Scler. 2013 Aug;19(9):1161-8.

Huen I, Morris DM, Wright C, Parker GJ, Sibley CP, Johnstone ED, Naish JH, R1 and R2 * changes in the human placenta in response to maternal oxygen challenge. Magn Reson Med. 2013 Nov;70(5):1427-33.

Bozzali M, Parker GJ, Spanò B, Serra L, Giulietti G, Perri R, Magnani G, Marra C, G Vita M, Caltagirone C, Cercignani M, Brain tissue modifications induced by cholinergic therapy in Alzheimer's disease. Hum Brain Mapp. 2013 Dec;34(12):3158-67.

Leach MO, Morgan B, Tofts PS, Buckley DL, Huang W, Horsfield MA, Chenevert TL, Collins DJ, Jackson A, Lomas D, Whitcher B, Clarke L, Plummer R, Judson I, Jones R, Alonzi R, Brunner T, Koh DM, Murphy P, Waterton JC, Parker G, Graves MJ, Scheenen TW, Redpath TW, Orton M, Karczmar G, Huisman H, Barentsz J, Padhani A, Experimental Cancer Medicine Centres Imaging Network Steering Committee., Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging. Eur Radiol. 2012 Jul;22(7):1451-64.

O'Connor JP, Jackson A, Parker GJ, Roberts C, Jayson GC, Dynamic contrast-enhanced MRI in clinical trials of antivascular therapies. Nat Rev Clin Oncol. 2012 Feb 14;9(3):167-77.

Banerji A, Naish JH, Watson Y, Jayson GC, Buonaccorsi GA, Parker GJ, DCE-MRI model selection for investigating disruption of microvascular function in livers with metastatic disease. J Magn Reson Imaging. 2012 Jan;35(1):196-203.

O'Connor JP, Rose CJ, Jackson A, Watson Y, Cheung S, Maders F, Whitcher BJ, Roberts C, Buonaccorsi GA, Thompson G, Clamp AR, Jayson GC, Parker GJ, DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6. Br J Cancer. 2011 Jun 28;105(1):139-45.

Mitchell CL, O'Connor JP, Roberts C, Watson Y, Jackson A, Cheung S, Evans J, Spicer J, Harris A, Kelly C, Rudman S, Middleton M, Fielding A, Tessier J, Young H, Parker GJ, Jayson GC, A two-part phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics. Cancer Chemother Pharmacol. 2011 Sep;68(3):631-41.

Roberts C, Little R, Watson Y, Zhao S, Buckley DL, Parker GJ, The effect of blood inflow and B(1)-field inhomogeneity on measurement of the arterial input function in axial 3D spoiled gradient echo dynamic contrast-enhanced MRI. Magn Reson Med. 2011 Jan;65(1):108-19.

Naish JH, Hutchinson CE, Caunce A, Roberts C, Waterton JC, Hockings PD, Taylor CJ, Parker GJ, Multiple-bolus dynamic contrast-enhanced MRI in the pancreas during a glucose challenge. J Magn Reson Imaging. 2010 Sep;32(3):622-8.

Kershaw LE, Naish JH, McGrath DM, Waterton JC, Parker GJ, Measurement of arterial plasma oxygenation in dynamic oxygen-enhanced MRI. Magn Reson Med. 2010 Dec;64(6):1838-42.

Williams TG, Holmes AP, Waterton JC, Maciewicz RA, Hutchinson CE, Moots RJ, Nash AF, Taylor CJ, Anatomically corresponded regional analysis of cartilage in asymptomatic and osteoarthritic knees by statistical shape modelling of the bone. IEEE Trans Med Imaging. 2010 Aug;29(8):1541-59.

Mitchell CL, O'Connor JPB, Jackson A, Parker GJM, Roberts C, Watson Y, Cheung S, Davies K, Buonaccorsi GA, Clamp AR, Hasan J, Byrd L, Backen A, Dive C, Jayson GC, Identification of early predictive imaging biomarkers and their relationship to serological angiogenic markers in patients with ovarian cancer with residual disease following cytotoxic therapy. Ann Oncol. 2010 Oct;21(10):1982-1989.

Zee YK, O'Connor JP, Parker GJ, Jackson A, Clamp AR, Taylor MB, Clarke NW, Jayson GC, Imaging angiogenesis of genitourinary tumors. Nat Rev Urol. 2010 Feb;7(2):69-82.

O'Connor JP, Carano RA, Clamp AR, Ross J, Ho CC, Jackson A, Parker GJ, Rose CJ, Peale FV, Friesenhahn M, Mitchell CL, Watson Y, Roberts C, Hope L, Cheung S, Reslan HB, Go MA, Pacheco GJ, Wu X, Cao TC, Ross S, Buonaccorsi GA, Davies K, Hasan J, Thornton P, del Puerto O, Ferrara N, van Bruggen N, Jayson GC, Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging. Clin Cancer Res. 2009 Nov 1;15(21):6674-82.

Mills SJ, Soh C, Rose CJ, Cheung S, Zhao S, Parker GJ, Jackson A, Candidate biomarkers of extravascular extracellular space: a direct comparison of apparent diffusion coefficient and dynamic contrast-enhanced MR imaging--derived measurement of the volume of the extravascular extracellular space in glioblastoma multiforme. AJNR Am J Neuroradiol. 2010 Mar;31(3):549-53.

Rose CJ, Mills SJ, O'Connor JP, Buonaccorsi GA, Roberts C, Watson Y, Cheung S, Zhao S, Whitcher B, Jackson A, Parker GJ, Quantifying spatial heterogeneity in dynamic contrast-enhanced MRI parameter maps. Magn Reson Med. 2009 Aug;62(2):488-99.

O'Connor JP, Naish JH, Parker GJ, Waterton JC, Watson Y, Jayson GC, Buonaccorsi GA, Cheung S, Buckley DL, McGrath DM, West CM, Davidson SE, Roberts C, Mills SJ, Mitchell CL, Hope L, Ton NC, Jackson A, Preliminary study of oxygen-enhanced longitudinal relaxation in MRI: a potential novel biomarker of oxygenation changes in solid tumors. Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1209-15.

Naish JH, Kershaw LE, Buckley DL, Jackson A, Waterton JC, Parker GJ, Modeling of contrast agent kinetics in the lung using T1-weighted dynamic contrast-enhanced MRI. Magn Reson Med. 2009 Jun;61(6):1507-14.

McGrath DM, Bradley DP, Tessier JL, Lacey T, Taylor CJ, Parker GJ, Comparison of model-based arterial input functions for dynamic contrast-enhanced MRI in tumor bearing rats. Magn Reson Med. 2009 May;61(5):1173-84.

Mills SJ, Soh C, O'Connor JP, Rose CJ, Buonaccorsi GA, Cheung S, Zhao S, Parker GJ, Jackson A, Tumour enhancing fraction (EnF) in glioma: relationship to tumour grade. Eur Radiol. 2009 Jun;19(6):1489-98.

O'Connor JP, Naish JH, Jackson A, Waterton JC, Watson Y, Cheung S, Buckley DL, McGrath DM, Buonaccorsi GA, Mills SJ, Roberts C, Jayson GC, Parker GJ, Comparison of normal tissue R1 and R*2 modulation by oxygen and carbogen. Magn Reson Med. 2009 Jan;61(1):75-83.

O'Connor JP, Jackson A, Asselin MC, Buckley DL, Parker GJ, Jayson GC, Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives. Lancet Oncol. 2008 Aug;9(8):766-76.

Roberts C, Parker GJ, Rose CJ, Watson Y, O'Connor JP, Stivaros SM, Jackson A, Rushton VE, Glandular function in Sjögren syndrome: assessment with dynamic contrast-enhanced MR imaging and tracer kinetic modeling--initial experience. Radiology. 2008 Mar;246(3):845-53.

Ton NC, Parker GJ, Jackson A, Mullamitha S, Buonaccorsi GA, Roberts C, Watson Y, Davies K, Cheung S, Hope L, Power F, Lawrance J, Valle J, Saunders M, Felix R, Soranson JA, Rolfe L, Zinkewich-Peotti K, Jayson GC, Phase I evaluation of CDP791, a PEGylated di-Fab' conjugate that binds vascular endothelial growth factor receptor 2. Clin Cancer Res. 2007 Dec 1;13(23):7113-8.

O'Connor JP, Jayson GC, Jackson A, Ghiorghiu D, Carrington BM, Rose CJ, Mills SJ, Swindell R, Roberts C, Mitchell CL, Parker GJ, Enhancing fraction predicts clinical outcome following first-line chemotherapy in patients with epithelial ovarian carcinoma. Clin Cancer Res. 2007 Oct 15;13(20):6130-5.

O'Connor JP, Jackson A, Buonaccorsi GA, Buckley DL, Roberts C, Watson Y, Cheung S, McGrath DM, Naish JH, Rose CJ, Dark PM, Jayson GC, Parker GJ, Organ-specific effects of oxygen and carbogen gas inhalation on tissue longitudinal relaxation times. Magn Reson Med. 2007 Sep;58(3):490-6.

Carr JP, Buckley DL, Tessier J, Parker GJ, What levels of precision are achievable for quantification of perfusion and capillary permeability surface area product using ASL? Magn Reson Med. 2007 Aug;58(2):281-9.

Jackson A, O'Connor JP, Parker GJ, Jayson GC, Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging. Clin Cancer Res. 2007 Jun 15;13(12):3449-59.

Davies GR, Hadjiprocopis A, Altmann DR, Chard DT, Griffin CM, Rashid W, Parker GJ, Tofts PS, Kapoor R, Thompson AJ, Miller DH, Normal-appearing grey and white matter T1 abnormality in early relapsing-remitting multiple sclerosis: a longitudinal study. Mult Scler. 2007 Mar;13(2):169-77.

Mullamitha SA, Ton NC, Parker GJ, Jackson A, Julyan PJ, Roberts C, Buonaccorsi GA, Watson Y, Davies K, Cheung S, Hope L, Valle JW, Radford JA, Lawrance J, Saunders MP, Munteanu MC, Nakada MT, Nemeth JA, Davis HM, Jiao Q, Prabhakar U, Lang Z, Corringham RE, Beckman RA, Jayson GC, Phase I evaluation of a fully human anti-alphav integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors. Clin Cancer Res. 2007 Apr 1;13(7):2128-35.

O'Connor JP, Jackson A, Parker GJ, Jayson GC, DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. Br J Cancer. 2007 Jan 29;96(2):189-95.

Parker GJ, Roberts C, Macdonald A, Buonaccorsi GA, Cheung S, Buckley DL, Jackson A, Watson Y, Davies K, Jayson GC, Experimentally-derived functional form for a population-averaged high-temporal-resolution arterial input function for dynamic contrast-enhanced MRI. Magn Reson Med. 2006 Nov;56(5):993-1000.

Buonaccorsi GA, Roberts C, Cheung S, Watson Y, O'Connor JP, Davies K, Jackson A, Jayson GC, Parker GJ, Comparison of the performance of tracer kinetic model-driven registration for dynamic contrast enhanced MRI using different models of contrast enhancement. Acad Radiol. 2006 Sep;13(9):1112-23.

Roberts C, Buckley DL, Parker GJ, Comparison of errors associated with single- and multi-bolus injection protocols in low-temporal-resolution dynamic contrast-enhanced tracer kinetic analysis. Magn Reson Med. 2006 Sep;56(3):611-9.

Buonaccorsi GA, Roberts C, Cheung S, Watson Y, Davies K, Jackson A, Jayson GC, Parker GJ, Tracer kinetic model-driven registration for dynamic contrast enhanced MRI time series. Med Image Comput Comput Assist Interv. 2005;8(Pt 1):91-8.

Roberts C, Issa B, Stone A, Jackson A, Waterton JC, Parker GJ, Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies. J Magn Reson Imaging. 2006 Apr;23(4):554-63.

Patankar TF, Haroon HA, Mills SJ, Balériaux D, Buckley DL, Parker GJ, Jackson A, Is volume transfer coefficient (K(trans)) related to histologic grade in human gliomas? AJNR Am J Neuroradiol. 2005 Nov-Dec;26(10):2455-65.

Naish JH, Parker GJ, Beatty PC, Jackson A, Young SS, Waterton JC, Taylor CJ, Improved quantitative dynamic regional oxygen-enhanced pulmonary imaging using image registration. Magn Reson Med. 2005 Aug;54(2):464-9.

Buckley DL, Roberts C, Parker GJ, Logue JP, Hutchinson CE, Prostate cancer: evaluation of vascular characteristics with dynamic contrast-enhanced T1-weighted MR imaging--initial experience. Radiology. 2004 Dec;233(3):709-15.

Jayson GC, Parker GJ, Mullamitha S, Valle JW, Saunders M, Broughton L, Lawrance J, Carrington B, Roberts C, Issa B, Buckley DL, Cheung S, Davies K, Watson Y, Zinkewich-Péotti K, Rolfe L, Jackson A, Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume. J Clin Oncol. 2005 Feb 10;23(5):973-81.

Chard DT, Griffin CM, Rashid W, Davies GR, Altmann DR, Kapoor R, Barker GJ, Thompson AJ, Miller DH, Progressive grey matter atrophy in clinically early relapsing-remitting multiple sclerosis. Mult Scler. 2004 Aug;10(4):387-91.

Chard DT, Brex PA, Ciccarelli O, Griffin CM, Parker GJ, Dalton C, Altmann DR, Thompson AJ, Miller DH, The longitudinal relation between brain lesion load and atrophy in multiple sclerosis: a 14 year follow up study. J Neurol Neurosurg Psychiatry. 2003 Nov;74(11):1551-4.

Miller DH, Barkhof F, Frank JA, Parker GJ, Thompson AJ, Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain. 2002 Aug;125(Pt 8):1676-95.

Kapeller P, Brex PA, Chard D, Dalton C, Griffin CM, McLean MA, Parker GJ, Thompson AJ, Miller DH, Quantitative 1H MRS imaging 14 years after presenting with a clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2002 May;8(3):207-10.

Harris NG, Gauden V, Fraser PA, Williams SR, Parker GJ, MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemia. Magn Reson Imaging. 2002 Apr;20(3):221-30.

Parker GJ, Barker GJ, Tofts PS, Accurate multislice gradient echo T1 measurement in the presence of non-ideal RF pulse shape and RF field nonuniformity. Magn Reson Med. 2001 May;45(5):838-45.

Padhani AR, MacVicar AD, Gapinski CJ, Dearnaley DP, Parker GJ, Suckling J, Leach MO, Husband JE, Effects of androgen deprivation on prostatic morphology and vascular permeability evaluated with mr imaging. Radiology. 2001 Feb;218(2):365-74.

Tofts PS, Lloyd D, Clark CA, Barker GJ, Parker GJ, McConville P, Baldock C, Pope JM, Test liquids for quantitative MRI measurements of self-diffusion coefficient in vivo. Magn Reson Med. 2000 Mar;43(3):368-74.

Padhani AR, Gapinski CJ, Macvicar DA, Parker GJ, Suckling J, Revell PB, Leach MO, Dearnaley DP, Husband JE, Dynamic contrast enhanced MRI of prostate cancer: correlation with morphology and tumour stage, histological grade and PSA. Clin Radiol. 2000 Feb;55(2):99-109.

Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, Larsson HB, Lee TY, Mayr NA, Parker GJ, Port RE, Taylor J, Weisskoff RM, Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging. 1999 Sep;10(3):223-32.

Creamer P, Keen M, Zananiri F, Waterton JC, Maciewicz RA, Oliver C, Dieppe P, Watt I, Quantitative magnetic resonance imaging of the knee: a method of measuring response to intra-articular treatments. Ann Rheum Dis. 1997 Jun;56(6):378-81.

Parker GJ, Suckling J, Tanner SF, Padhani AR, Revell PB, Husband JE, Leach MO, Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics. J Magn Reson Imaging. 1997 May-Jun;7(3):564-74.

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